Rational design of siloxane-polyurethane elastomers for medical implants with passive anti-bacterial adhesion and hydrolytic stability
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Published on: March 8, 2019
Minghui Cui1,2, Xin Shi1, Guohui Tian1
1Key Laboratory of Bio-based Polymeric Materials Technology and Application of Zhejiang Province, Laboratory of Polymers and Composites, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China. chenjing@nimte.ac.cn.
Abstract:
A biocide-free passive defense polyurethane (PDMS-HTPB-SH-PU) with low surface energy achieves near-complete anti-bacterial adhesion (>99%), excellent hydrolytic stability, anti-calcification, cytocompatibility, and robust mechanics (tensile strength 17.4-25.7 MPa), overcoming implant-associated infections and degradation.
