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Updated: Jul 2, 2025

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Use of Recombinant Fusion Proteins in a Fluorescent Protease Assay Platform and Their In-gel Renaturation
Published on: January 16, 2019
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A non-peptide-based fluorescent probe capable of sensitively visualizing asparagine endopeptidase
Kang Li1, Yanxian Hou1, Jinliang Han1
1State Key Laboratory of Fine Chemicals, Frontiers Science Centre for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian 116024, China. fanjl@dlut.edu.cn.
Abstract:
The non-peptide-based fluorescent probe QMC11 is capable of specifically targeting asparagine endopeptidase (AEP) and imaging cellular endogenous AEP. The motion of the probe can be restricted by AEP to activate fluorescence while keeping a low background signal.

