Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Analysis of repetitive sequence elements containing tRNA-like sequences.

C B Lawrence, D P McDonnell, W J Ramsey

    Nucleic Acids Research
    |June 25, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Measurement of Protein Synthesis Rate in Rat by [<sup>11</sup>C]Leucine PET Imaging: Application to the TgF344-AD Model of Alzheimer's Disease.

    Molecular imaging and biology·2022
    Same author

    A hyperacute immune map of ischaemic stroke patients reveals alterations to circulating innate and adaptive cells.

    Clinical and experimental immunology·2020
    Same author

    Cystine addiction of triple-negative breast cancer associated with EMT augmented death signaling.

    Oncogene·2017
    Same author

    Cystine addiction of triple-negative breast cancer associated with EMT augmented death signaling.

    Oncogene·2016
    Same author

    LaeA and VeA are involved in growth morphology, asexual development, and mycotoxin production in Alternaria alternata.

    International journal of food microbiology·2016
    Same author

    Systemic inflammation affects reperfusion following transient cerebral ischaemia.

    Experimental neurology·2016
    Same journal

    Correction to 'scSuperAnnotator: A platform for benchmarking comparison and visualizing automated cellular annotation methods for scRNA-seq data'.

    Nucleic acids research·2026
    Same journal

    Correction to 'Differentiable partition function calculation for RNA'.

    Nucleic acids research·2026
    Same journal

    Deployment of non-canonical splicing in tunicate genomes is mediated by divergent U2AF function and changing m6A modification in U1 and U6 snRNA.

    Nucleic acids research·2026
    Same journal

    Bacillus subtilis DnaB forms multiple protein-protein interactions essential for DNA replication initiation.

    Nucleic acids research·2026
    Same journal

    Multiple forms of protein-protein and DNA binding are exhibited by BrxC from the BREX phage restriction system.

    Nucleic acids research·2026
    Same journal

    Biosynthesis of glycosylated 5-hydroxycytosine in the DNA of diverse viruses.

    Nucleic acids research·2026
    See all related articles

    Repetitive DNA sequences in various species resemble transfer RNA (tRNA) molecules. These tRNA-like elements likely originated from authentic tRNAs and form three distinct retroposon families.

    Area of Science:

    • Molecular Biology
    • Genomics
    • Evolutionary Biology

    Background:

    • Many repetitive DNA sequences across different species exhibit similarities to transfer RNA (tRNA) molecules.
    • Understanding the origin and evolution of these repetitive elements is crucial for deciphering genome organization and dynamics.

    Purpose of the Study:

    • To investigate the origin of repetitive sequence elements that show homology to tRNA.
    • To classify these tRNA-like elements into distinct groups based on sequence homology, organization, and species distribution.

    Main Methods:

    • Comparative sequence analysis of repetitive elements from diverse species.
    • Identification and characterization of tRNA-like sequences within these elements.
    • Phylogenetic and organizational analysis to group related elements.

    Related Experiment Videos

    Main Results:

    • Several repetitive sequence elements demonstrate significant sequence homology with tRNA molecules.
    • These tRNA-like sequences appear to have originated from authentic tRNA sequences.
    • The elements were classified into three distinct groups, each sharing extensive homology, similar organization, and unique species distribution.

    Conclusions:

    • The findings suggest that tRNA molecules are a source for the origin of certain repetitive DNA elements.
    • The three identified groups represent independent retroposon families that likely arose from tRNA sequences.
    • This provides insight into the evolutionary processes shaping eukaryotic genomes through retroposon formation.