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Updated: Jul 2, 2025

Induction of Microstreaming by Nonspherical Bubble Oscillations in an Acoustic Levitation System
Published on: May 9, 2021
A unifying Rayleigh-Plesset-type equation for bubbles in viscoelastic media
Alexandros T Oratis1, Kay Dijs1, Guillaume Lajoinie1
1Physics of Fluids Group, Max Planck Center for Complex Fluid Dynamics, Faculty of Science and Technology, Technical Medical (TechMed) Center, University of Twente, Enschede, The Netherlands.
This study presents a new model for microbubble dynamics in viscoelastic materials, crucial for ultrasound imaging and drug delivery. The model accurately predicts large deformations, advancing biomedical applications.
Area of Science:
- Biomedical Engineering
- Acoustics
- Materials Science
Background:
- Microbubble dynamics are vital for ultrasound imaging and drug delivery.
- Existing models for microbubbles in viscoelastic media have limitations regarding constitutive models and deformation size.
- Accurate modeling is needed for diverse biomedical applications.
Purpose of the Study:
- To derive a unifying equation for microbubble dynamics in viscoelastic media.
- To account for arbitrary complex moduli and large bubble deformations.
- To provide a more versatile model than previously available.
Main Methods:
- Extended the Rayleigh-Plesset equation using finite-strain theory.
- Developed a new viscoelastic Rayleigh-Plesset model.
- Validated the model against previous results and applied it to benchmark materials.
Main Results:
- Derived a unifying equation for microbubble dynamics in viscoelastic media.
- The model successfully accounts for large bubble deformations.
- Demonstrated the model's capability to predict microbubble behavior in various viscoelastic liquids and solids.
Conclusions:
- The new model offers a significant advancement for understanding microbubble behavior in complex viscoelastic environments.
- This work has broad implications for improving ultrasound-based biomedical applications.
- The derived equation provides a powerful tool for future research and development.
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