Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Analgesia and Pain Management01:25

Analgesia and Pain Management

623
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
623

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Peripheral Nerve Stimulation of the Sacral Lateral Branches for Sacroiliac Joint Pain: A Technical Report.

Pain practice : the official journal of World Institute of Pain·2026
Same author

Updated 2026 Comprehensive Evidence-Based Guidelines for Facet Joint Interventions in the Management of Chronic Spinal Pain: American Society of Interventional Pain Physicians (ASIPP) Guidelines.

Pain physician·2026
Same author

Neurovascular Compression Syndromes of Cranial Nerves: A Multidisciplinary Guide to Management.

Brain sciences·2026
Same author

A Systematic Review and Meta-Analysis of Randomized Controlled Trials of Epidural Regenerative Medicine Therapies in Managing Spinal Pain.

Current pain and headache reports·2026
Same author

The Utility of Caudal Epidural Steroid Injections: A Comprehensive Review.

Orthopedic reviews·2026
Same author

Radiofrequency ablation of C2-3 medial branches/third occipital nerve to treat cervicogenic headache.

Annals of palliative medicine·2026

Related Experiment Video

Updated: Jul 2, 2025

Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain
09:35

Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain

Published on: May 10, 2017

18.9K

Neuromodulation Techniques for Headache Management.

Noora Reffat1, Carolina Pusec2, Scott Price1

  • 1School of Medicine and Public Health, University of Wisconsin, Madison, WI 53705, USA.

Life (Basel, Switzerland)
|February 24, 2024
PubMed
Summary
This summary is machine-generated.

Neuromodulation offers a promising alternative for managing chronic cluster headaches and migraines. Techniques like peripheral nerve stimulation (PNS) and transcranial magnetic stimulation (TMS) effectively reduce headache frequency and pain intensity.

Keywords:
headachemigraineneuromodulationpain management

More Related Videos

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache
05:40

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Published on: July 29, 2021

7.9K
3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

18.2K

Related Experiment Videos

Last Updated: Jul 2, 2025

Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain
09:35

Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain

Published on: May 10, 2017

18.9K
Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache
05:40

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Published on: July 29, 2021

7.9K
3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

18.2K

Area of Science:

  • Neurology
  • Neurosurgery
  • Pain Management

Background:

  • Headaches, particularly migraines and chronic cluster headaches, significantly impact quality of life.
  • Neuromodulation presents a growing area of interest for non-pharmacological headache treatment.

Purpose of the Study:

  • To review current evidence on neuromodulation techniques for headache treatment.
  • To explore future applications of neuromodulation in managing migraines and chronic cluster headaches.

Main Methods:

  • A comprehensive literature search was conducted in PubMed (August 2023).
  • Systematic reviews published between 2022-2023 were prioritized, supplemented by primary literature.
  • Focused on four key neuromodulation techniques: PNS, TMS, DBS, and SCS.

Main Results:

  • Neuromodulation has established utility in treating chronic cluster headaches and migraines.
  • Key techniques include peripheral nerve stimulation (PNS), transcranial magnetic stimulation (TMS), deep brain stimulation (DBS), and spinal cord stimulation (SCS).
  • Evidence indicates a reduction in headache frequency and/or pain intensity across studies.

Conclusions:

  • Neuromodulation is a viable alternative treatment for refractory chronic cluster headaches and migraines.
  • Further research may expand the role of neuromodulation in headache management.
  • Consideration of adverse effects and costs is important for clinical implementation.