Application of Non-Ligation Technique in Thyroidectomy.

Area of Science:

• Endocrinology
• Surgical Oncology
• General Surgery

Background:

• Papillary thyroid micro-carcinoma (PTMC) is the smallest form of thyroid cancer.
• Surgical techniques for PTMC aim to minimize invasiveness and complications.
• Traditional ligation methods in thyroidectomy can prolong operative time and affect parathyroid function.

Purpose of the Study:

• To compare the efficacy and safety of a non-ligation technique versus traditional ligation in thyroidectomy for PTMC.
• To evaluate the impact of each surgical technique on operative time, postoperative bleeding, and biochemical markers.

Main Methods:

• A retrospective analysis of patients undergoing thyroidectomy for PTMC.
• Data collected included patient demographics, operative details, and postoperative levels of parathyroid hormone (PTH) and blood calcium.
• Comparison of outcomes between the non-ligation and traditional ligation groups.

Main Results:

• The non-ligation technique significantly reduced operative time compared to traditional ligation (69.36 ± 1.38 vs. 82.72 ± 2.12 minutes, P < .0001).
• Postoperative serum calcium and PTH levels showed less variation with the non-ligation technique.
• While PTH levels were temporarily lower in the non-ligation group (7.20±1.99 vs. 20.78±3.78, P < .01), all biochemical indicators normalized within three weeks.

Conclusions:

• The non-ligation technique offers a significant advantage by reducing thyroidectomy operation time for PTMC patients.
• Temporary fluctuations in PTH and blood calcium levels associated with the non-ligation technique are transient and resolve within three weeks.
• The non-ligation technique presents a favorable and beneficial treatment option for PTMC management.