Related Experiment Video
Updated: Jul 2, 2025

Murine Skin Transplantation
Published on: January 16, 2008
Achieving self-sufficiency in skin allograft: A Singapore experience
Si Jack Chong1, Zhen Luan Low1, Jialin Yick1
1Department of Plastic, Reconstructive and Aesthetic Surgery, Singapore General Hospital, Outram Road, Singapore 169608, Singapore.
Aim:
This paper describes how Singapore achieved skin allograft self-sufficiency in 2017 by adopting 5 key strategies in 2012.
Background:
Singapore General Hospital (SGH) established its own allograft recovery programme in 1998 but was still dependent on overseas allograft procurement.
Key Strategies:
RESULTS: The allograft recovery programme expanded from 4 to all 20 institutions. Donor referrals increased by 42.9% from 35 in 2014 to over 50 currently. Donor numbers increased by 210%, rising from 4.5 per year before 2015 to an average of 14 per year from 2015 to 2022. The total allografts recovered increased by 223%, climbing from 13,000 to 42,000 annually. Cryopreservation was adopted, extending shelf life to 5.5 years and doubling storage capacity to more than 140,000 cm2 in 2022.
Conclusion:
Singapore achieved skin allograft self-sufficiency with no overseas procurement since 2017.
Related Concept Videos
Clinical Applications of Epidermal Stem Cells
Tissue Transplantation
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

