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Updated: May 4, 2026

Preparation of DNA-crosslinked Polyacrylamide Hydrogels
Published on: August 27, 2014
Delayed complications from polyacrylamide gel breast fillers: a case report
1Department of Surgery, Austin Health, 145 Studley Road, Heidelberg, 3084, Victoria, Australia.
Abstract:
In the late nineties, polyacrylamide gel (PAAG) gained popularity in China as a soft tissue filler for breast augmentation and contouring, but was banned 10 years later due to the increasing incidence of complications. We report a case of PAAG complication that occurred 20 years after the initial injection, where the patient had significant unilateral breast swelling and an intracapsular lesion. Surgical removal of the breast filler and immediate breast reconstruction was successfully performed, and histology confirmed a benign breast lesion. These findings highlight the importance of clinical awareness of PAAG breast filler complications.

