Related Experiment Video
Updated: Jul 2, 2025
08:37
Isolation, Fixation, and Immunofluorescence Imaging of Mouse Adrenal Glands
Published on: October 2, 2018
23.9K
Current insight into the transient X-zone in the adrenal gland cortex
Yuan Kang1, Karly Laprocina1, Huifei Sophia Zheng1
1Department of Anatomy, Physiology & Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.
Vitamins and Hormones
|February 26, 2024
Summary
Mouse models reveal the adrenal gland X-zone
Area of Science:
- Endocrinology
- Developmental Biology
- Comparative Anatomy
Background:
- The mouse adrenal X-zone is a transient structure, remnant of the fetal adrenal cortex.
- Its functional significance is less understood compared to the analogous human fetal zone.
- X-zone development exhibits sexual dimorphism and varies with genetic background.
Conclusions:
- Mouse models are crucial for understanding X-zone biology.
- These models provide insights into the molecular regulation of adrenocortical cell development and regression.
- Further research using these models can clarify the X-zone's functional role.
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