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Updated: May 5, 2026
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Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
Published on: July 20, 2022
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Prognostic value of right atrial strains in arrhythmogenic right ventricular cardiomyopathy
Jin-Yu Zheng1, Bing-Hua Chen1, Rui Wu1
1Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, People's Republic of China.
Insights Into Imaging
|February 27, 2024
Summary
Right atrial strain parameters, including reservoir strain (RARS) and booster strain (RABS), are independent predictors of adverse cardiac events in arrhythmogenic right ventricular cardiomyopathy (ARVC). These measures offer incremental prognostic value beyond traditional risk factors for ARVC patients.
Area of Science:
- Cardiology
- Cardiovascular Imaging
- Genetics
Background:
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart condition.
- Fibrofatty infiltration of the heart muscle leads to adverse cardiac events.
- Right atrial (RA) function is increasingly recognized for its prognostic importance.
Purpose of the Study:
- To analyze the prognostic value of right atrial (RA) strain in patients with ARVC.
- To determine if RA strain parameters can predict adverse cardiac events in ARVC.
- To assess the incremental predictive capability of RA strain.
Main Methods:
- Cardiac magnetic resonance (CMR) imaging was used to assess RA strain in 105 ARVC participants.
- Adverse cardiac events were defined as sudden cardiac death, survived cardiac arrest, or appropriate ICD intervention.
- Cox regression and Kaplan-Meier analyses evaluated the association between RA strain and endpoints, with C-index, NRI, and IDI assessing incremental value.
Main Results:
- Reduced RA strain parameters were observed in patients experiencing adverse events.
- Impaired RA reservoir strain (RARS) and booster strain (RABS) were linked to a higher risk of cardiac events.
- RARS and RABS independently predicted adverse events, improving upon conventional risk factors and CMR predictors.
Conclusions:
- RA reservoir strain (RARS) and booster strain (RABS) are independent predictors of adverse cardiac events in ARVC.
- These RA strain parameters offer significant incremental prognostic value.
- Cardiologists should consider RA strain assessment for better long-term outcome prediction and clinical management in ARVC.
Keywords:
Arrhythmogenic right ventricular cardiomyopathyArrhythmogenic right ventricular dysplasiaMagnetic resonance imagingRight atrial functionStrainMore Related Videos
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