Damage evaluation of craniofacial localized scleroderma using magnetic resonance imaging
Xuda Ma1, Jiuzuo Huang1, Huadan Xue2
1Department of Plastic Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
Quantitative Imaging in Medicine and Surgery
|February 28, 2024
Summary
Magnetic resonance imaging (MRI) reliably quantifies damage in localized scleroderma (LoS) of the face. This objective tool aids in assessing craniofacial LoS, improving evaluation accuracy.
Area of Science:
- Dermatology
- Radiology
- Medical Imaging
Background:
- Localized scleroderma (LoS) is an autoimmune condition causing craniofacial deformities.
- Objective assessment of craniofacial LoS is challenging.
- Magnetic resonance imaging (MRI) is explored as a damage assessment tool.
Purpose of the Study:
- To analyze tissue involvement in craniofacial LoS using MRI.
- To evaluate the efficacy of MRI for assessing craniofacial LoS.
Main Methods:
- Cross-sectional study of 28 patients with craniofacial LoS.
- Clinical, MRI, and ultrasound assessments were performed.
- MRI was compared with ultrasound and clinical scores.
Main Results:
- MRI showed high correlation and agreement with ultrasound (r=0.916).
- The accumulated soft tissue atrophy index (ASTAI) correlated well with clinical aesthetic indices (r=0.921).
- MRI revealed inaccuracies in 38.6% of clinical scores and detected neurological changes in one patient.
Conclusions:
- MRI is a reliable tool for quantifying craniofacial LoS damage.
- MRI offers an objective method for evaluating overall craniofacial LoS.
Keywords:
Localized scleroderma (LoS)Parry-Romberg syndrome (PRS)craniofacial morpheaen coup de sabre (ECDS)magnetic resonance imaging (MRI)
