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Related Experiment Video

Updated: Jul 2, 2025

Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting
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Person-centered methods to advance developmental psychopathology.

Elizabeth D Handley1, Erinn B Duprey1,2, Justin Russotti1

  • 1Mt. Hope Family Center, University of Rochester, Rochester, NY, USA.

Development and Psychopathology
|February 28, 2024
PubMed
Summary

Person-centered methods advance developmental psychopathology research. A childhood neuroendocrine profile of high cortisol and low DHEA predicted better adult functioning, highlighting the importance of integrated analysis.

Keywords:
DHEAcortisoldevelopmental psychopathologymaltreatmentperson-centered methods

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Area of Science:

  • Developmental psychopathology
  • Neuroendocrinology
  • Psychological science

Background:

  • Dante Cicchetti advanced key principles in developmental psychopathology, including typical/atypical development interplay, multifinality, equifinality, resilience, and multi-level analysis.
  • Person-centered data analytic methods are proposed as ideal for advancing these developmental psychopathology tenets.

Purpose of the Study:

  • To demonstrate the utility of person-centered analytic methods in developmental psychopathology research.
  • To investigate childhood neuroendocrine regulation patterns and their prospective links with adult functioning.

Main Methods:

  • Employed a novel empirical study utilizing person-centered data analytic methods.
  • Examined childhood neuroendocrine profiles, specifically diurnal cortisol and DHEA levels.
  • Assessed prospective links between childhood neuroendocrine patterns and emerging adult functioning.

Main Results:

  • A specific childhood neuroendocrine profile characterized by high diurnal cortisol and low diurnal DHEA was uniquely associated with more adaptive functioning in emerging adulthood.
  • Person-centered methods effectively identified this distinct neuroendocrine profile and its long-term implications.

Conclusions:

  • Person-centered data analytic methods are highly suitable for advancing developmental psychopathology research and theory.
  • Childhood neuroendocrine regulation, particularly the cortisol/DHEA balance, plays a significant role in predicting adaptive functioning in emerging adulthood.
  • Findings underscore the value of integrating multiple levels of analysis for a comprehensive understanding of developmental trajectories.