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Prenatal caffeine consumption and neurobehavioral disorders - A systematic review
Aleksander Brandão Santana1, Lídia Emmanuela Wiazowski Spelta2, Joselin Valeska Martinez-Sobalvarro3
1Department of Food and Drugs, Faculty of Pharmaceutical Sciences, Federal University of Alfenas, Alfenas, MG, Brazil.
Reproductive Toxicology (Elmsford, N.Y.)
|February 28, 2024
Summary
Limited evidence suggests prenatal caffeine exposure may be linked to neurobehavioral deficits, but more research is needed. The current review found insufficient data to confirm a definitive association between caffeine intake during pregnancy and neurodevelopmental disorders.
Area of Science:
- Neuroscience
- Developmental Psychology
- Public Health
Background:
- Gestational caffeine exposure has been tentatively linked to adverse outcomes, but robust evidence remains scarce.
- Prenatal exposure to substances is a critical factor influencing child neurodevelopment.
- Understanding the impact of maternal caffeine consumption on fetal neurobehavioral development is crucial.
Conclusions:
- Current evidence is insufficient to definitively conclude that prenatal caffeine exposure causes neurobehavioral disorders.
- Study limitations, including heterogeneity, variable quality, and confounding factors, contribute to uncertainty.
- Further high-quality research is necessary to clarify the relationship between gestational caffeine intake and child neurodevelopmental outcomes.
Keywords:
Attention Deficit Hyperactivity DisorderBehavioral developmentCaffeineIntellectual developmentMaternal ExposureNeurobehavioral ManifestationsPrenatal Exposure Delayed EffectsPrenatal caffeine consumptionMore Related Videos
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