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Applications of Graphene Field Effect Biosensors for Biological Sensing
Kiana Aran1,2,3,4,5, Brett Goldsmith6, Maryam Moarefian7
1Shu Chien-Gene Lay Department of Bioengineering, Jacobs School of Engineering, University of California, San Diego, La Jolla, CA, USA. karan@ucsd.edu.
None:
This chapter provides a comprehensive overview of the principles, applications, and advancements in graphene field-effect transistor (gFET) biosensors for biological sensing. The unique properties of graphene that make it ideal for biosensing, including its high conductivity, chemical stability, and ability to facilitate label-free detection, will be discussed. The chapter also explores various applications of gFET biosensors, from detecting pH and salinity changes to complex protein-protein interactions and DNA/RNA sensing. It also addresses the challenges and future directions in gFET biosensor technology, emphasizing the need for scalable manufacturing, sophisticated surface chemistry, and the integration of multiomics approaches to enhance biosensing capabilities.
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