Related Experiment Video
Updated: Jul 2, 2025

13:35
Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
2.6K
Ectopic Breast Cancer Arising within an Axillary Lymph Node.
Kei Toshima1, Tadahiko Shien1, Midori Filiz Nishimura2
1Department of Breast and Endocrine Surgery, Okayama University Hospital.
Acta Medica Okayama
|February 29, 2024
Summary
This case study details a rare instance of ectopic breast cancer found in an axillary lymph node. Diagnosis and treatment were challenging due to its unusual presentation, mimicking metastasis.
Area of Science:
- Oncology
- Surgical Pathology
- Radiology
Background:
- Ectopic breast tissue can occur along the embryonic milk lines, including the axilla.
- Malignancies arising in ectopic breast tissue are rare, posing diagnostic challenges.
- Axillary lymph node involvement is common in breast cancer but primary ectopic breast cancer in a lymph node is exceptionally uncommon.
Observation:
- A 65-year-old woman presented with diagnosed breast cancer and axillary lymph node metastasis.
- Post-surgical pathology revealed invasive ductal carcinoma within an axillary lymph node, originating from ectopic mammary tissue.
Findings:
- The malignancy was identified as invasive ductal carcinoma within ectopic breast tissue in an axillary lymph node.
- Distinguishing this ectopic breast cancer from metastatic disease presented diagnostic challenges.
Implications:
- This case highlights the importance of considering ectopic breast tissue in differential diagnoses for axillary masses.
- Accurate pathological identification is crucial for appropriate treatment of rare ectopic breast cancers.
Related Concept Videos
Detailed Structure and Function of Lymph Nodes
1.6K
Lymph nodes are bean-shaped structures that cluster along the lymphatic vessels in the inguinal, axillary, and cervical regions. Each node is divided into compartments by a capsule that extends trabeculae inward.
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...
1.6K
Metastasis
5.5K
Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
5.5K

