Use of the Indigo CAT RX aspiration system during percutaneous coronary intervention

Area of Science:

• Cardiology
• Interventional Cardiology
• Medical Devices

Background:

• Limited studies have investigated the Indigo CAT RX Aspiration System for percutaneous coronary intervention.
• Mechanical aspiration thrombectomy is a key treatment for acute myocardial infarction.

Purpose of the Study:

• To evaluate the clinical, angiographic, and procedural outcomes of the Indigo CAT RX system in patients undergoing mechanical aspiration thrombectomy.
• To assess the safety and efficacy of the Indigo CAT RX system in a real-world setting.

Main Methods:

• Retrospective analysis of 83 patients (85 lesions) treated with the Indigo CAT RX system between January 2019 and April 2023.
• Inclusion criteria: patients undergoing mechanical aspiration thrombectomy for coronary artery disease.
• Data collected: patient demographics, clinical presentation, procedural details, angiographic outcomes, and 30-day follow-up for major adverse cardiac events.

Main Results:

• The most common indications were ST-segment elevation myocardial infarction (66.2%) and non-ST-segment elevation myocardial infarction (26.5%).
• High rates of final Thrombolysis In Myocardial Infarction (TIMI) flow grade 3 (76%) and Myocardial Blush Grade (MBG) 3 (46%) were achieved.
• Technical success was 88.9% for Indigo CAT RX alone. No device-related serious adverse events were reported. Major adverse cardiac events occurred in 8.5% of patients within 30 days, including stroke (1.3%), myocardial infarction (1.3%), cardiac death (6.1%), and cardiogenic shock (7.5%).

Conclusions:

• The Indigo CAT RX system demonstrates high technical success in mechanical aspiration thrombectomy for acute coronary syndromes.
• The system is associated with an acceptable risk of complications, including stroke, in this patient cohort.