Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Step-Growth Polymerization: Overview01:03

Step-Growth Polymerization: Overview

3.6K
Step-growth or condensation polymerization is a stepwise reaction of bi or multifunctional monomers to form long-chain polymers. As all the monomers are reactive, most of the monomers are consumed at the early stages of the reaction to form small chains of reactive oligomers, which then combine to form long polymer chains in the late stages. Hence, the reaction has to proceed for a long time to achieve high molecular weight polymers.
Many natural and synthetic polymers are produced by...
3.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Integrated physiological, transcriptomic and widely targeted metabolomic analyses reveal the underlying mechanism of cold stress response in the panicle apical abortion line J876 derived from Oryza rufipogon.

Plant physiology and biochemistry : PPB·2026
Same author

Development of Novel Estradiol-Indole Hybrids Targeting SERT and ERβ as Potential Antidepressants.

Journal of medicinal chemistry·2026
Same author

Optimization of Extrusion Three-Dimensional Printing Liquid Silicone Rubber: Managing Thermal History and Modification for Improved Printability.

ACS omega·2026
Same author

Genetically Engineered Membrane-Mimetic Liposome-Wrapped Violet Phosphorus Nanoplatform for Targeted Synergistic Ferroptosis/Photothermal/Immunotherapy of Hepatocellular Carcinoma.

ACS applied materials & interfaces·2026
Same author

BMSCs regulate RGS3 expression in ovarian stromal cells to improve ovarian stromal fibrosis and angiogenic microenvironment in cyclophosphamide-induced premature ovarian failure.

Stem cell research & therapy·2026
Same author

A compact low-power valveless piezoelectric micropump with a nested rectification structure.

Lab on a chip·2026
Same journal

Optical photothermal infrared (O-PTIR) micro-spectroscopic characterisation of breast cancer cell lines: a comparative molecular profile of MCF7, MDA-MB-231, and SKBR3 cells.

The Analyst·2026
Same journal

A novel electrochemiluminescence sensor using Lu-Au@Ni-MOF for ultra-sensitive detection of permethrin.

The Analyst·2026
Same journal

Sensitive detection of meat spoilage VOCs and visual monitoring of freshness <i>via</i> a UiO-66-NH<sub>2</sub>@MR nanocomposite-based colorimetric paper sensor.

The Analyst·2026
Same journal

AuNPs/rGO-enhanced molecularly imprinted field-effect transistor sensor for highly selective detection of lactic acid in sweat.

The Analyst·2026
Same journal

Surface-engineered biochar-Cu-BTC hybrid for ultrasensitive dual detection of uric acid and nitrite.

The Analyst·2026
Same journal

Metabolic profiles of MK-3984 (SARM) in zebrafish using ultra high performance liquid chromatography Q extractive HF hybrid quadrupole orbitrap mass spectrometry (UPLC-QE-HF-MS) for doping control.

The Analyst·2026
See all related articles

Related Experiment Video

Updated: May 2, 2026

Preparation of Light-responsive Membranes by a Combined Surface Grafting and Postmodification Process
12:00

Preparation of Light-responsive Membranes by a Combined Surface Grafting and Postmodification Process

Published on: March 21, 2014

11.8K

A one-step process for multi-gradient wettability modification on a polymer surface.

Xinxin Li1, Xinyu Mao1, Xudong Li1

  • 1Department of Mechanical Engineering, Dalian University of Technology, Dalian, Liaoning, China. chongl@dlut.edu.cn.

The Analyst
|February 29, 2024
PubMed
Summary
This summary is machine-generated.

Controlled gradient oxygen plasma modification (CGPM) enables selective surface wettability changes on poly(dimethylsiloxane) (PDMS) microfluidic devices. This technique enhances D-dimer detection sensitivity and speed.

More Related Videos

Selective Area Modification of Silicon Surface Wettability by Pulsed UV Laser Irradiation in Liquid Environment
08:48

Selective Area Modification of Silicon Surface Wettability by Pulsed UV Laser Irradiation in Liquid Environment

Published on: November 9, 2015

8.3K
Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications
09:22

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications

Published on: August 28, 2015

19.2K

Related Experiment Videos

Last Updated: May 2, 2026

Preparation of Light-responsive Membranes by a Combined Surface Grafting and Postmodification Process
12:00

Preparation of Light-responsive Membranes by a Combined Surface Grafting and Postmodification Process

Published on: March 21, 2014

11.8K
Selective Area Modification of Silicon Surface Wettability by Pulsed UV Laser Irradiation in Liquid Environment
08:48

Selective Area Modification of Silicon Surface Wettability by Pulsed UV Laser Irradiation in Liquid Environment

Published on: November 9, 2015

8.3K
Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications
09:22

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications

Published on: August 28, 2015

19.2K

Area of Science:

  • Materials Science
  • Surface Chemistry
  • Microfluidics

Background:

  • Poly(dimethylsiloxane) (PDMS) microfluidic devices require surface modification for tunable wettability and flow control.
  • Existing methods for PDMS surface modification are limited to altering single areas at a time.

Purpose of the Study:

  • To introduce a novel Controlled Gradient Oxygen Plasma Modification (CGPM) technique for creating spatially controlled wettability gradients on PDMS surfaces.
  • To investigate the influence of mask properties on CGPM effectiveness.
  • To demonstrate the application of CGPM in an integrated microfluidic device for enhanced D-dimer detection.

Main Methods:

  • Developed CGPM by layering porous resin masks on PDMS surfaces to control oxygen plasma density.
  • Utilized COMSOL plasma module simulations to analyze the effect of mask porosity, hole size, distribution, and distance on wettability.
  • Characterized CGPM performance using contact angle measurements.
  • Integrated the CGPM technique into a microfluidic device for D-dimer identification.

Main Results:

  • CGPM achieved a continuous change in PDMS surface contact angle from 8.77° to 76.98° within 25 seconds.
  • Simulations provided insights into optimizing mask parameters for precise wettability control.
  • The D-dimer assay in the integrated device was completed in 10 minutes, showing a dynamic range of 1-1000 ng mL⁻¹.
  • Observed a 78.3% peak and 31.1% average increase in fluorescence signal for D-dimer detection compared to standard treatments.

Conclusions:

  • CGPM offers a versatile and efficient method for creating tunable wettability gradients on PDMS surfaces.
  • The technique significantly improves the performance of microfluidic assays, as demonstrated by enhanced D-dimer detection.
  • CGPM holds promise for advancing microfluidic device applications in diagnostics and beyond.