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Retinal Vasoproliferative Tumours in Uveitis.
Arshee S Ahmed1, Parthopratim Dutta Majumder1, Amala Elizabeth1
1Department of Uvea, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Ocular Immunology and Inflammation
|February 29, 2024
Summary
Retinal vasoproliferative tumours (RVPTs) are rare peripheral lesions. Early diagnosis and targeted therapy, including corticosteroids and cryotherapy or laser, lead to successful regression in most cases.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Uveitis
Background:
- Retinal vasoproliferative tumours (RVPTs) are uncommon peripheral retinal lesions.
- RVPTs are frequently associated with intermediate uveitis.
Purpose of the Study:
- To characterize a cohort of patients diagnosed with RVPTs.
- To describe the clinical presentation, management, and outcomes of RVPTs in a tertiary eye care institute in India.
Main Methods:
- Retrospective chart review of patients with RVPTs.
- Data collected included patient demographics, clinical features, treatment modalities, and visual outcomes.
Main Results:
- A cohort of 17 patients (18 eyes) with RVPTs was analyzed.
- The majority of patients were male, with a mean age of 36.3 years.
- Commonly associated condition was intermediate uveitis; treatments included corticosteroids, immunosuppressives, cryotherapy, or laser photocoagulation.
- Successful regression of RVPTs was achieved in all but one patient, with no significant change in best-corrected visual acuity post-treatment.
Conclusions:
- RVPTs, though rare, require prompt diagnosis and tailored treatment.
- Effective management strategies can lead to favorable long-term outcomes with minimal recurrence.
- Early intervention is crucial for preventing vision loss associated with RVPTs.

