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Planning for the future of maternal immunization: Building on lessons learned from the COVID-19 pandemic

Dana Meaney-Delman1, Sarah Carroll2, Kara Polen1

  • 1Division of Birth Defects and Infant Disorders, Centers for Disease Control and Prevention, Atlanta, GA, United States.

Vaccine
|February 29, 2024
PubMed

Insights

Pregnant individuals faced severe COVID-19 illness and lacked vaccine data initially. Suboptimal vaccine uptake highlights the need for better maternal vaccination strategies.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Maternal Health

Background:

  • The COVID-19 pandemic disproportionately affected pregnant individuals, leading to severe illness and adverse pregnancy outcomes.
  • Pregnant individuals were excluded from initial COVID-19 vaccine trials, creating a data gap for safety and efficacy.
  • Misinformation regarding vaccine safety and infertility reduced vaccine confidence among pregnant populations.

Purpose of the Study:

  • To analyze the impact of the COVID-19 pandemic on pregnant individuals.
  • To examine the challenges and trends in COVID-19 vaccine acceptance among pregnant populations.
  • To derive insights for future maternal vaccination strategies.

Main Methods:

  • Review of pandemic-related health data concerning pregnant individuals.
  • Analysis of COVID-19 vaccine uptake and confidence trends in pregnant populations.
  • Examination of factors influencing vaccine hesitancy and acceptance.

Main Results:

  • Pregnant individuals experienced higher risks of severe COVID-19 and adverse pregnancy outcomes.
  • Initial COVID-19 vaccine hesitancy was prevalent due to lack of data and misinformation.
  • Vaccine acceptance increased as safety data emerged, but remained suboptimal and varied by race/ethnicity.

Conclusions:

  • The COVID-19 pandemic underscored the vulnerability of pregnant individuals to infectious diseases.
  • Addressing misinformation and ensuring timely data are crucial for maternal vaccine confidence.
  • Lessons learned can inform improved strategies for future maternal immunizations.

Keywords:
COVID-19Maternal immunizationVaccine

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