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Visual processing speed and its association with future dementia development in a population-based prospective
Ahmet Begde1, Thomas Wilcockson2, Carol Brayne3
1School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, LE11 3TU, UK. a.begde@lboro.ac.uk.
Scientific Reports
|February 29, 2024
Summary
Reduced visual processing speed, particularly for complex tasks, is linked to a higher risk of future dementia diagnosis. Combining visual tests with cognitive assessments may improve early dementia detection.
Area of Science:
- Neuroscience
- Ophthalmology
- Gerontology
Background:
- Visual processing deficits are common in dementia, suggesting potential for early screening.
- The Visual Sensitivity Test (VST) assesses visual processing speed.
Purpose of the Study:
- To investigate the association between visual processing speed (simple and complex VST) and future dementia risk.
- To compare the predictive utility of VST with established cognitive screening tests.
Main Methods:
- Utilized data from the EPIC-Norfolk Prospective Population Cohort Study (n=8623).
- Employed Cox regression analyses to assess the relationship between VST scores and dementia diagnosis.
- Compared VST performance with Hopkins Verbal Learning Test (HVLT) and Short-Form Memory and Executive Function Screening Examination (SF-EMSE).
Main Results:
- Lower simple VST scores correlated with increased dementia risk (HR 1.39, P<0.01).
- Lower complex VST scores showed a stronger association with dementia risk (HR 1.56, P<0.01).
- Complex VST demonstrated greater sensitivity to dementia risk factors compared to HVLT and SF-EMSE.
Conclusions:
- Reduced complex visual processing speed is a significant indicator of future dementia risk.
- Integrating visual processing tests with other cognitive assessments may enhance dementia risk identification.
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