Related Experiment Video
Updated: May 1, 2026

10:10
Quantifying Cognitive Decrements Caused by Cranial Radiotherapy
Published on: October 18, 2011
12.7K
Grade 5 Radiation Necrosis After Whole-Brain Radiation Therapy
Andrew Tam1, Yun Rose Li2, Terence Williams2
1Department of Radiation Oncology, City of Hope National Cancer Center, Duarte, California.
Practical Radiation Oncology
|March 2, 2024
Abstract
None:
Whole-brain radiation treatment is often considered for patients with leptomeningeal disease. There are limited reports of the development of radiation necrosis after whole-brain radiation treatment and fewer associating the presence of germline mutations with risk. We present a case report to highlight the need for consideration of radiosensitizing mutations when recommending radiation therapy.

