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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Sensory Functions of the Skin01:16

Sensory Functions of the Skin

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The skin is the largest organ of the human body and plays a crucial role in our sensory perception. It contains a vast network of sensory receptors that contribute to the skin's protective function by perceiving physical, biological, and environmental cues and generating relevant responses.
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
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Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

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The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
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Accessory Structures of the Skin: Nails01:05

Accessory Structures of the Skin: Nails

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Nails are one of the important accessory structures of the skin. They are hard, protective structures that cover the dorsal surface of the distal phalanges of fingers and toes. Nails are composed of specialized keratinized cells and serve various functions, including protection, sensation, and manual dexterity.
The main components of a nail include the following.
Nail Plate: The nail plate is the visible portion of the nail that extends beyond the fingertips or toes. It is a hard, translucent...
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Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
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Related Experiment Video

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Author Spotlight: Advancing Research in Corneal Opacity Treatment and Regeneration
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Skin tumors and trephines.

A G Spaulding

    Ophthalmic Surgery
    |May 1, 1979
    PubMed
    Summary

    Glaucoma and corneal trephines can be repurposed for eyelid lesion biopsies, simplifying both incisional and excisional procedures. This method utilizes the trephine for wound creation and, in excisions, for graft preparation, streamlining surgical techniques.

    Area of Science:

    • Ophthalmology
    • Dermatology
    • Surgical Techniques

    Background:

    • Eyelid lesions require accurate diagnosis through biopsy.
    • Current biopsy methods can be complex or require specialized instruments.

    Purpose of the Study:

    • To evaluate the utility of outmoded glaucoma and corneal trephines for eyelid lesion biopsies.
    • To assess the feasibility of using trephines for both incisional and excisional biopsy techniques.

    Main Methods:

    • Utilized glaucoma and corneal trephines to obtain incisional biopsies from eyelid lesions.
    • Employed the same trephines for excisional biopsies, including graft preparation for wound closure.

    Main Results:

    • Trephines successfully obtained incisional biopsies from eyelid lesions.

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  • Excisional biopsies were performed, and wounds were closed using grafts prepared with the trephine.

    • Conclusions:

    • Outmoded glaucoma and corneal trephines offer a viable alternative for eyelid lesion biopsies.
    • This technique simplifies surgical procedures for eyelid lesion diagnosis and management.