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Renal Corpuscle01:20

Renal Corpuscle

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The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
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Related Experiment Video

Updated: Jul 1, 2025

An Efficient Sieving Method to Isolate Intact Glomeruli from Adult Rat Kidney
10:14

An Efficient Sieving Method to Isolate Intact Glomeruli from Adult Rat Kidney

Published on: November 1, 2018

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Isolated renal aspergilloma.

Hasan Al-Ibraheem1, George Shaker1, Stella Roushias1

  • 1NHS Wales Aneurin Bevan University Health Board, Newport, United Kingdom.

Urology Case Reports
|March 4, 2024
PubMed
Summary
This summary is machine-generated.

Isolated renal aspergilloma, a rare fungal kidney infection, presents challenges. Percutaneous nephrolithotomy (PCNL) combined with antifungals effectively treated a patient with kidney stones and this infection.

Keywords:
Renal aspergillosisRenal aspirgillomaRenal fungal ball

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Use of a Hanging-weight System for Isolated Renal Artery Occlusion
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Last Updated: Jul 1, 2025

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Area of Science:

  • Nephrology
  • Mycology
  • Surgical Urology

Background:

  • Renal aspergilloma, a fungal infection confined to the kidneys, is exceptionally rare.
  • It presents significant diagnostic and therapeutic difficulties.
  • This case involves a patient with pre-existing urolithiasis, type II diabetes, and chronic kidney disease.

Observation:

  • The patient presented with isolated renal aspergilloma linked to obstructing uric acid renal tract calculi.
  • Initial treatment with ureteroscopy showed limited success in clearing the fungal infection and stones.

Findings:

  • Percutaneous nephrolithotomy (PCNL) was successfully employed to surgically remove both the fungal balls and calculi.
  • The patient received peri-operative oral and systemic antifungal medications.
  • Post-operative irrigation of the renal collecting system with amphotericin was administered.

Implications:

  • This case highlights PCNL as a viable and effective treatment for complex isolated renal aspergilloma.
  • Successful management underscores the importance of a multi-modal approach combining surgical intervention and antifungal therapy.
  • The findings contribute to understanding rare fungal infections of the kidney and their management in patients with comorbidities.