Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of blood-flow velocity and direction on coagulation zone symmetry induced by microwave ablation using ECO antenna.

International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·2026
Same author

Recalled experiences of death: need for empirical research without prejudice.

Nature reviews. Neurology·2026
Same author

Analytical model of large-diameter spherical-like catheter for pulsed field ablation in treating cardiac arrhythmias.

Physics in medicine and biology·2025
Same author

Body Size Modulates the Impact of the Dispersive Patch Position During Radiofrequency Cardiac Ablation.

Bioengineering (Basel, Switzerland)·2025
Same author

Impact of Intrapericardial Fluid on Lesion Size During Epicardial Radiofrequency Ablation: A Computational Study.

Journal of cardiovascular development and disease·2025
Same author

Thermal side effects during pulsed field ablation: an analysis using computer modelling.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2025

Related Experiment Video

Updated: Jul 1, 2025

Author Spotlight: Improving Lesion Contiguity in Pulmonary Vein Isolation via Proactive Esophageal Cooling
05:43

Author Spotlight: Improving Lesion Contiguity in Pulmonary Vein Isolation via Proactive Esophageal Cooling

Published on: April 19, 2024

1.0K

Proactive esophageal cooling during laser cardiac ablation: A computer modeling study.

Tatiana Gomez Bustamante1, Marcela Mercado Montoya1, Enrique Berjano2

  • 1In Silico Science & Engineering S.A.S., Medellin, Colombia.

Lasers in Surgery and Medicine
|March 4, 2024
PubMed
Summary

Proactive esophageal cooling (PEC) effectively prevents esophageal injury during laser ablation for atrial fibrillation (AF). This method significantly reduces thermal damage to the esophagus without compromising therapeutic cardiac lesion formation.

Keywords:
atrial fibrillationatrioesophageal fistulaesophageal coolinglaser ablationlaser balloonmathematical modeling

More Related Videos

Reduced Procedure Time and Variability with Active Esophageal Cooling During Radiofrequency Ablation for Atrial Fibrillation
04:58

Reduced Procedure Time and Variability with Active Esophageal Cooling During Radiofrequency Ablation for Atrial Fibrillation

Published on: August 25, 2022

2.2K
Cooling or Warming the Esophagus to Reduce Esophageal Injury During Left Atrial Ablation in the Treatment of Atrial Fibrillation
06:25

Cooling or Warming the Esophagus to Reduce Esophageal Injury During Left Atrial Ablation in the Treatment of Atrial Fibrillation

Published on: March 15, 2020

9.7K

Related Experiment Videos

Last Updated: Jul 1, 2025

Author Spotlight: Improving Lesion Contiguity in Pulmonary Vein Isolation via Proactive Esophageal Cooling
05:43

Author Spotlight: Improving Lesion Contiguity in Pulmonary Vein Isolation via Proactive Esophageal Cooling

Published on: April 19, 2024

1.0K
Reduced Procedure Time and Variability with Active Esophageal Cooling During Radiofrequency Ablation for Atrial Fibrillation
04:58

Reduced Procedure Time and Variability with Active Esophageal Cooling During Radiofrequency Ablation for Atrial Fibrillation

Published on: August 25, 2022

2.2K
Cooling or Warming the Esophagus to Reduce Esophageal Injury During Left Atrial Ablation in the Treatment of Atrial Fibrillation
06:25

Cooling or Warming the Esophagus to Reduce Esophageal Injury During Left Atrial Ablation in the Treatment of Atrial Fibrillation

Published on: March 15, 2020

9.7K

Area of Science:

  • Cardiovascular Medicine
  • Biomedical Engineering
  • Medical Physics

Background:

  • Laser ablation is a growing treatment for atrial fibrillation (AF).
  • Atrioesophageal injury is a serious complication of AF ablation.
  • Proactive esophageal cooling (PEC) is known to reduce esophageal injury during radiofrequency ablation.

Purpose of the Study:

  • To evaluate the protective effects of PEC during laser ablation for AF.
  • To determine if PEC impacts therapeutic lesion formation in the atrium.
  • To assess the risk of esophageal injury with varying tissue thicknesses during laser ablation.

Main Methods:

  • Developed 3D mathematical models of atrial and esophageal walls.
  • Simulated laser-tissue interaction using Beer-Lambert's law.
  • Calculated temperature distribution with Pennes' Bioheat equation and tissue damage with the Arrhenius equation.

Main Results:

  • PEC significantly lowered esophageal temperatures by ~22°C and atrial wall temperatures by ~9°C.
  • Esophageal transmural lesions were absent with PEC.
  • Esophageal thermal damage occurred only without PEC and with proximity ≤3.5mm.

Conclusions:

  • PEC effectively mitigates esophageal injury risk during laser ablation for AF.
  • PEC does not significantly degrade the quality or depth of cardiac lesions.
  • Thermal latency is a factor in lesion formation and potential collateral damage.