Related Experiment Video
Updated: Jul 1, 2025

Systematic Hearing Performance Evaluation Process for Adolescents with Cochlear Implantation at Early Ages
Published on: March 24, 2023
Individual Patient Comorbidities and Effect on Cochlear Implant Performance
Sabina Dang1, Dorina Kallogjeri, Karmela Dizdar1
1Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine in St. Louis, Missouri.
Preoperative comorbidities impact cochlear implant (CI) speech outcomes. While all patients show improvement, those with severe comorbidities achieve less benefit compared to those without. This highlights the importance of assessing comorbidities for CI success.
Area of Science:
- Audiology
- Otolaryngology
- Neurosurgery
Background:
- Cochlear implantation (CI) is a common treatment for severe to profound hearing loss.
- Preoperative patient health status, including comorbidities, may influence CI outcomes.
- Understanding this association can help manage patient expectations and surgical planning.
Purpose of the Study:
- To investigate the relationship between preoperative comorbidities and speech understanding after cochlear implantation.
- To determine if the severity of comorbidities affects speech outcomes in adult CI recipients.
Main Methods:
- Retrospective cohort study of 976 adult patients undergoing cochlear implantation (CI) between 2015 and 2022.
- Comorbidities were assessed using the Adult Comorbidity Evaluation 27 (ACE-27) scale based on preoperative anesthesia notes.
- Speech outcomes, including Consonant-Nucleus-Consonant (CNC) and AzBio Sentence scores (quiet and +10 dB SNR), were evaluated at 3, 6, and 12 months post-implantation.
Main Results:
- Of 560 eligible patients, 20% had no comorbidities, 36.4% mild, 28.8% moderate, and 14.8% severe.
- All comorbidity groups demonstrated clinically meaningful speech improvement over 12 months.
- Patients with severe comorbidities showed significantly poorer speech outcomes compared to those with no comorbidities (e.g., AzBio Quiet: 52.3 vs 32.5 difference).
Conclusions:
- Preoperative comorbidities, as measured by ACE-27, are significantly associated with cochlear implant speech performance.
- While patients with severe comorbidities still benefit from CI, their overall speech outcomes are less favorable than those without comorbidities.
- Comorbidity assessment is crucial for predicting and managing expectations regarding CI outcomes.
Related Concept Videos
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History

