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Acquired Aquagenic Syringeal Keratoderma Following COVID-19 Infection
Bryce W Polascik1, Samantha P Karklins1, Matthew C Johnson2
1Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Hand (New York, N.Y.)
|March 5, 2024
Summary
Aquagenic syringeal keratoderma (ASK) is rare in males. A case report details a man who developed ASK after COVID-19, with symptoms resolving after botulinum toxin treatment.
Area of Science:
- Dermatology
- Infectious Diseases
- Allergy and Immunology
Background:
- Aquagenic syringeal keratoderma (ASK) is a rare condition causing palmar wrinkling after water exposure.
- While typically associated with females, this case explores a male presentation.
Observation:
- A 24-year-old atopic male developed ASK symptoms 3 months post-COVID-19 infection.
- Symptoms included bilateral palmar edema and papules upon water contact.
- Previous treatments like topical aluminum chloride were ineffective.
Findings:
- Botulinum toxin injections into both palms resulted in sustained symptom resolution for 7 months.
- The patient had a history of atopy, including atopic dermatitis and food allergies.
Implications:
- This case suggests a potential link between COVID-19 infection and the development of ASK in predisposed individuals.
- ASK may represent a novel manifestation of post-acute sequelae of SARS-CoV-2 (PASC) or long COVID.
- Further research is needed to explore the association between viral infections, atopy, and ASK.
Keywords:
ASKCOVID-19aquagenic syringeal keratodermaaquagenic wrinklingbotulinum toxinhand wrinklingpalmsMore Related Videos
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