Central Auditory Processing Impairment in Renal Failure

This study is the first to investigate central auditory processing impairment in patients with slight decrease in renal function (PSR), who had no risk factors, evidence of renal injury, and albuminuria. The aim was to determine the scores of dichotic digits test (DDT) and word-in-noise perception (WINP) test in PSR. The survey was cross-sectional-comparative. The case group consisted of 30 PSR, with an estimated glomerular filtration rate of 60-90 mL/min at 1.73 m2. The control group consisted of 60 normal participants. They were matched with the case group based on sex, education level, dominant hand and age. The measures were the 28-item general health questionnaire, mini-mental state examination, Petersburg sleep quality index, acoustic immittance assessment, pure tone audiometry, speech reception threshold evaluation, DDT and WINP test. Both groups had normal stress levels, night sleep, mental states, and hearing thresholds. The mean scores of the WINP test in the right and left ears of the case group were significantly different from the control group (Pv_Right = 0.026, Pv_Left = 0.029 ). The mean difference of DDT scores in the right and left ears of the case group compared to the control group showed significant difference (Pv_Right = 0.039, Pv_Left = 0.048 ). Therefore, slight decrease in renal function can be one of the causes of central auditory processing impairment. Affected patients with normal hearing thresholds may have difficulty in discrimination the pitch of words, and speech perception in competing situations.

The online version contains supplementary material available at 10.1007/s12070-023-04345-5.