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Related Concept Videos

Dementia01:30

Dementia

113
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
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Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

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Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
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Related Experiment Video

Updated: Jul 1, 2025

A High Throughput, Multiplexed and Targeted Proteomic CSF Assay to Quantify Neurodegenerative Biomarkers and Apolipoprotein E Isoforms Status
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Democratising access to dementia research.

Ruth Dobson, Nirandeep Rehill, Rimona S Weil

    Advances in Clinical Neuroscience & Rehabilitation : ACNR
    |March 6, 2024
    PubMed
    Summary

    Access to dementia research in the UK is unequal. Dedicated staff and resources, alongside streamlined processes, are key to improving dementia research participation and overcoming structural barriers.

    Area of Science:

    • Gerontology
    • Neuroscience
    • Public Health

    Background:

    • The aging UK population faces a growing prevalence of dementia.
    • Accelerating dementia research is a priority, but access remains inequitable.
    • Understanding barriers to dementia research participation is crucial.

    Purpose of the Study:

    • To examine current access to dementia research.
    • To identify enabling factors and barriers to research participation.
    • To propose solutions for equitable access.

    Main Methods:

    • Qualitative analysis of factors influencing dementia research access.
    • Identification of common barriers and facilitators to recruitment.
    • Review of existing infrastructure and governance frameworks.

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    Main Results:

    • Dedicated personnel significantly drive high recruitment rates.
    • Structural issues, particularly lack of time and resources, are primary barriers.
    • Inequitable access is not due to lack of willingness or knowledge.

    Conclusions:

    • Leveraging existing infrastructure and efficient governance can improve access.
    • Research must ensure accessible inclusion/exclusion criteria for diverse patient groups.
    • Increased resources are essential for effective on-the-ground recruitment.