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Sodium citrate buffer improves pazopanib solubility and absorption in gastric acid-suppressed rat model

Huda Jassim Muhammad1, Tsutomu Shimada2, Arimi Fujita2

  • 1Department of Clinical Pharmacokinetics, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8641, Japan; Department of Clinical Pharmacy, College of Pharmacy, Karbala University, Karbala, 56001, Iraq.

Drug Metabolism and Pharmacokinetics
|March 6, 2024
PubMed

Keywords:
AbsorptionAcidic beverageCitratePazopanibPharmacokineticsSolubility

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