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Neural control of blinking.

Matteo Bologna1, Giulia Paparella1, Josep Valls-Solé2

  • 1Department of Human Neurosciences, Sapienza, University of Rome, Rome, Italy; IRCCS Neuromed, Pozzilli, IS, Italy.

Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology
|March 6, 2024
PubMed
Summary
This summary is machine-generated.

Blinking involves coordinated eyelid muscle activity, controlled by brain circuits. This review details the neural pathways governing reflexive, spontaneous, and voluntary blinks.

Keywords:
BlinkingMotor controlNeurophysiology

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Area of Science:

  • Neuroscience
  • Ophthalmology
  • Motor Control

Background:

  • Blinking is a crucial motor act for eye protection and lubrication.
  • It involves complex, coordinated muscle actions of the eyelids.
  • Neural control mechanisms for blinking are distributed across the central nervous system.

Purpose of the Study:

  • To provide a comprehensive overview of the neural control of blinking.
  • To detail the anatomical and physiological underpinnings of blinking.
  • To elucidate the regulation of different blinking types (reflexive, spontaneous, voluntary).

Main Methods:

  • Literature review of anatomical and physiological studies on blinking.
  • Analysis of neural circuits involved in motor control of the eyelids.
  • Description of infra-nuclear and supra-nuclear control mechanisms.

Main Results:

  • Blinking relies on reciprocal activation of orbicularis oculi and levator palpebrae superioris muscles.
  • Neural control involves overlapping circuits in cortical, subcortical, and brainstem structures.
  • Distinct and shared neural pathways govern different blinking types.

Conclusions:

  • Understanding the neural control of blinking is essential for neurological and ophthalmological research.
  • The study highlights the intricate neural coordination underlying this fundamental motor act.
  • Further research into these circuits may inform treatments for blinking disorders.