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mTORC2: The "Ace in the Hole" for a Broader Control of Epileptic Seizures?

Shuo Zhang1, Xiongfeng Guo2, Wei Huang1

  • 1Department of Pharmacy, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, 310006, China.

Neuroscience Bulletin
|March 7, 2024
PubMed
Abstract

No abstract available in PubMed .

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Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
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