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Blood Typing

Blood Typing

Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target antigens A,...

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Updated: Jul 10, 2026

Enumeration of Major Peripheral Blood Leukocyte Populations for Multicenter Clinical Trials Using a Whole Blood Phenotyping Assay

Enumeration of Major Peripheral Blood Leukocyte Populations for Multicenter Clinical Trials Using a Whole Blood Phenotyping Assay

Published on: September 16, 2012

NONDOMESTIC FELID ABC BLOOD PHENOTYPING, GENOTYPING, AND CROSSMATCHING.

Lily Parkinson¹, Henrike Kuder², Alexandra Kehl²

¹College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA, Lily.Parkinson@czs.org.

Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians

|March 7, 2024

Summary

This summary is machine-generated.

Blood typing in nondomestic felids is crucial for transfusions. Standard domestic cat methods, including point-of-care kits and CMAH genotyping, are unreliable for these species, necessitating crossmatching.

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Published on: June 21, 2018

Area of Science:

Veterinary Medicine
Immunology
Genetics

Background:

Assessing blood types and transfusion compatibility in nondomestic felids is vital for conservation and veterinary care.
Domestic cats (Felis catus) have an ABC blood group system, but its application to nondomestic felids is not well-established.

Purpose of the Study:

To evaluate the efficacy of standard domestic cat blood typing methods (point-of-care kits and CMAH genotyping) in various nondomestic felid species.
To determine blood type prevalence and identify incompatibilities within and between nondomestic felid species and with domestic cats.

Main Methods:

Blood samples from 162 individuals across 18 nondomestic felid species were analyzed.
Traditional laboratory typing, point-of-care testing, and CMAH genotyping for B and C (AB) variants were performed.
Crossmatching was conducted between nondomestic felids and with domestic cats.

Main Results:

Discrepancies were observed between point-of-care and traditional typing results.
None of the tested nondomestic felids possessed the specific CMAH variants found in domestic cats for types B and C (AB).
Significant crossmatch incompatibilities were identified, with only 27% of domestic-to-nondomestic cat crossmatches being compatible.

Conclusions:

Point-of-care typing kits and CMAH genotyping may not accurately determine ABC blood types in nondomestic felids.
Pre-transfusion crossmatching is essential to ensure compatible blood transfusions in nondomestic felids.