Transversus Thoracic Muscle Plane Block For Postoperative Pain in Pediatric Cardiac Surgery: A Systematic Review And

Yi-Yang Cui1, Zi-Qing Xu2, Huai-Jing Hou2

  • 1First School of Clinical Medicine, Gansu University of Chinese Medicine, Chengguan District, Lanzhou, China.

Insights

Transversus thoracic muscle plane block (TTMPB) may reduce pain, opioid use, and intensive care unit (ICU) stay in pediatric cardiac surgery patients. This novel block offers potential benefits for managing surgical pain in children.

Area of Science:

  • Anesthesiology and Pain Management
  • Pediatric Cardiac Surgery
  • Regional Anesthesia Techniques

Background:

  • Pediatric cardiac surgery often involves significant postoperative pain, impacting recovery.
  • Effective analgesia is crucial to prevent a pain continuum into the postoperative period.
  • The efficacy of Transversus Thoracic Muscle Plane Block (TTMPB) for pediatric cardiac surgery pain is not well-established.

Approach:

  • A systematic review and meta-analysis was performed.
  • Searched major databases (PubMed, Embase, Web of Science, CENTRAL, WanFang, CNKI) up to November 2023.
  • Evaluated evidence certainty using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach.

Key Points:

  • Six studies with 601 pediatric patients (2 months to 12 years) were analyzed.
  • TTMPB demonstrated potential reductions in postoperative pain scores at 12 and 24 hours.
  • Significant decreases were observed in intraoperative and postoperative opioid consumption.
  • Reduced intensive care unit (ICU) length of stay and extubation time were noted.
  • Evidence certainty ranged from very low to low.

Conclusions:

  • TTMPB shows promise in improving pain management for pediatric cardiac surgery.
  • The technique may decrease opioid requirements and shorten ICU stays.
  • Further high-quality research is needed to confirm these findings due to low evidence certainty.
Abstract

Related Concept Videos

Skeletal Muscle Relaxants: Therapeutic Uses01:31

Skeletal Muscle Relaxants: Therapeutic Uses

Skeletal muscle relaxants are used to relax muscle tone and alleviate painful muscle contractions. However, the choice of skeletal muscle relaxants depends on the duration of the surgical procedure in order to minimize potential side effects. Skeletal muscle relaxants like neuromuscular blocking agents [NMBAs] are commonly employed as adjuvants alongside general anesthetics in clinical settings. NMBAs are also used to maintain controlled ventilation during surgery of the larynx or pharynx...
482
Nondepolarizing (Competitive) Neuromuscular Blockers: Pharmacological Actions01:27

Nondepolarizing (Competitive) Neuromuscular Blockers: Pharmacological Actions

Nondepolarizing neuromuscular blockers prevent the membrane depolarization of muscle cells and inhibit muscle contraction. These are usually administered with anesthetics to achieve complete muscle relaxation. Upon administration, these drugs first block the small, rapidly contracting muscles of the face and hands, followed by the larger muscles of the trunk and the intercostal muscles. The diaphragm is the last muscle to be affected.
Although all competitive neuromuscular blockers are designed...
420
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
413
Local Anesthetics: Clinical Application as Spinal Anesthesia01:11

Local Anesthetics: Clinical Application as Spinal Anesthesia

Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
627