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Transversus Thoracic Muscle Plane Block For Postoperative Pain in Pediatric Cardiac Surgery: A Systematic Review And
Yi-Yang Cui1, Zi-Qing Xu2, Huai-Jing Hou2
1First School of Clinical Medicine, Gansu University of Chinese Medicine, Chengguan District, Lanzhou, China.
Insights
Transversus thoracic muscle plane block (TTMPB) may reduce pain, opioid use, and intensive care unit (ICU) stay in pediatric cardiac surgery patients. This novel block offers potential benefits for managing surgical pain in children.
Area of Science:
- Anesthesiology and Pain Management
- Pediatric Cardiac Surgery
- Regional Anesthesia Techniques
Background:
- Pediatric cardiac surgery often involves significant postoperative pain, impacting recovery.
- Effective analgesia is crucial to prevent a pain continuum into the postoperative period.
- The efficacy of Transversus Thoracic Muscle Plane Block (TTMPB) for pediatric cardiac surgery pain is not well-established.
Approach:
- A systematic review and meta-analysis was performed.
- Searched major databases (PubMed, Embase, Web of Science, CENTRAL, WanFang, CNKI) up to November 2023.
- Evaluated evidence certainty using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach.
Key Points:
- Six studies with 601 pediatric patients (2 months to 12 years) were analyzed.
- TTMPB demonstrated potential reductions in postoperative pain scores at 12 and 24 hours.
- Significant decreases were observed in intraoperative and postoperative opioid consumption.
- Reduced intensive care unit (ICU) length of stay and extubation time were noted.
- Evidence certainty ranged from very low to low.
Conclusions:
- TTMPB shows promise in improving pain management for pediatric cardiac surgery.
- The technique may decrease opioid requirements and shorten ICU stays.
- Further high-quality research is needed to confirm these findings due to low evidence certainty.
Objectives:
Pediatric patients undergoing cardiac surgery usually experience significant surgical pain. Additionally, the effect of poor surgical analgesia creates a pain continuum that extends to the postoperative period. Transversus thoracic muscle plane block (TTMPB) is a novel plane block technique that can provide analgesia to the anterior chest wall. The analgesic role of TTMPB in pediatric cardiac surgery is still uncertain. A meta-analysis was conducted to determine the analgesic efficacy of this procedure.
Design And Setting:
Systematic review and meta-analysis. PubMed, Embase, Web of Science, CENTRAL, WanFang Data, and the China National Knowledge Infrastructure were searched to November 2023, and the Grading of Recommendations Assessment, Development, and Evaluation approach was followed to evaluate the certainty of evidence.
Participants:
Eligible studies enrolled pediatric patients from 2 months to 12 years old scheduled to undergo cardiac surgery, and randomized them to receive a TTMPB or no block/sham block.
Measurements And Main Results:
Six studies that enrolled 601 pediatric patients were included. Low-certainty evidence from randomized trials showed that, compared with no block or sham block, TTMPB in pediatric patients undergoing cardiac surgery may reduce postoperative modified objective pain score at 12 hours (weighted mean difference [WMD] -2.20, 95% CI -2.73 to -1.68) and 24 hours (WMD -1.76, 95% CI -2.09 to -1.42), intraoperative opioid consumption (WMD -3.83, 95% CI -5.90 to -1.76 μg/kg), postoperative opioid consumption (WMD -2.51, 95% CI -2.84 to -2.18 μg/kg), length of intensive care unit (ICU) stay (WMD -5.56, 95% CI -8.30 to -2.83 hours), and extubation time (WMD -2.13, 95% CI -4.21 to -0.05 hours). Retrospective studies provided very low certainty that the results were consistent with the randomized trials.
Conclusion:
Very low- to low-certainty evidence showed that TTMPB in pediatric patients undergoing cardiac surgery may reduce postoperative pain, opioid consumption, ICU length of stay, and extubation time.
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