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Related Concept Videos

Proofreading01:43

Proofreading

Synthesis of new DNA molecules starts when DNA polymerase links nucleotides together in a sequence that is complementary to the template DNA strand. DNA polymerase has a higher affinity for the correct base to ensure fidelity in DNA replication. The DNA polymerase furthermore proofreads during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.Errors during Replication Are Corrected by the DNA Polymerase EnzymeGenomic DNA is synthesized in...
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Biochemical reactions are occurring constantly in cells, converting starting substances to different products, usually with the help of enzymes that speed the reactions. Without enzymes, it would take far too long for most reactions to occur to be useful to the cell!
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Social psychologists have documented that feeling good about ourselves and maintaining positive self-esteem is a powerful motivator of human behavior (Tavris & Aronson, 2008). In the United States, members of the predominant culture typically think very highly of themselves and view themselves as good people who are above average on many desirable traits (Ehrlinger, Gilovich, & Ross, 2005). Often, our behavior, attitudes, and beliefs are affected when we experience a threat to our...

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Related Experiment Video

Updated: Jun 16, 2026

Author Spotlight: Training of Laboratory Animals for Gentle and Stress-Free Handling
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A structured, journal-led peer-review mentoring program enhances peer review training.

Ariel Maia Lyons-Warren1, Whitley W Aamodt2, Kathleen M Pieper3

  • 1Department of Pediatrics, Section of Neurology; Clinical Care Center, Baylor College of Medicine, Houston, USA. lyonswar@bcm.edu.

Research Integrity and Peer Review
|March 8, 2024
PubMed
Summary

A structured mentored peer-review program significantly improved trainee skills and confidence in manuscript review. This training enhances understanding of publication science and leads to high mentor satisfaction.

Keywords:
JournalologyMentorshipPeer reviewResearchSurveys and QuestionnairesTraining

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Area of Science:

  • Scientific Publishing
  • Academic Medicine
  • Research Integrity

Background:

  • Peer review is crucial for scientific advancement but lacks standardized training.
  • Current peer review training methods are often unorganized and understudied.
  • A structured approach to peer review training is needed to improve quality and consistency.

Purpose of the Study:

  • To evaluate the effectiveness of a structured mentored peer-review program.
  • To assess improvements in peer review skills using quantitative and qualitative measures.
  • To determine the impact of mentorship on trainee understanding of the publication process.

Main Methods:

  • A pre-post intervention study involving 55 mentees across 5 cohorts (2020-2023).
  • Mentees underwent 2 mentored reviews over 6 months, with pre- and post-program assessments.
  • Outcomes included the modified Review Quality Index (mRQI), mentee self-perception surveys, and mentor satisfaction.

Main Results:

  • Mentees showed significant improvement in mRQI scores post-program (median 31 vs. 26.6).
  • Self-perceived understanding of review and editorial processes, and confidence in manuscript review, increased significantly (p < 0.0001).
  • Mentors reported high satisfaction with the program, enjoyment, and interest in repeat participation.

Conclusions:

  • A 6-month structured mentored peer-review program effectively enhances peer review training.
  • The program improves the quality of reviews as measured by mRQI and boosts mentee confidence.
  • High mentor satisfaction indicates the program's feasibility and positive impact on the scientific community.