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Updated: Jul 1, 2025

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
Prop-2-ynyl 3-meth-oxy-4-(prop-2-yn-yloxy)benzoate
Cresten Moodley1, Alfred Muller1, Yonas H Belay1
1Synthesis and Catalysis Research Centre, Department of Chemical Sciences, University of Johannesburg (APK Campus), PO Box 524, Auckland Park, Johannesburg, 2006, South Africa.
Abstract:
The title compound, C14H12O4, comprises of two crystallographically independent mol-ecules in the asymmetric unit, linked via C-H⋯O inter-actions to form dimeric entities. The allylic groups are twisted out of the phenyl planes with dihedral angles varying between 7.92 (13) and 25.42 (8)°. In the crystal, the packing follows a zigzag pattern along the c-axis direction. The absolute configuration of the sample could not be determined reliably.
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