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Updated: Jul 7, 2026

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
1,1'-(2,2-Di-phenyl-ethene-1,1-di-yl)bis-(3,5-dimethyl-1H-pyrazol-2-ium) dichloride
1Institut für Organische Chemie, Technische Universität Bergakademie Freiberg, Leipziger Str. 29, 09599 Freiberg, Germany.
Abstract:
The title compound, C24H26N4 2+·2Cl-, crystallizes in the triclinic space group P1. The ethene derivative is substituted by two phenyl groups in 2-position and two 3,5-di-methyl-pyrazolinium units in 1-position, which makes this alkene into a dication. Two chloride ions act as counter-ions in the crystal structure and are linked via N-H⋯Cl and C-H⋯Cl inter-actions with the alkene. The crystal structure features a three-dimensional network stabilized by N-H⋯Cl, C-H⋯Cl and C-H⋯π inter-actions. The crystal structure contains disordered solvent mol-ecules, corresponding to 43 electrons in a void volume of 102 Å3, which could not be modeled satisfactorily. Reverse Fourier transform methods were used to account for the unknown pore content.
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