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Mapping Genome-wide Accessible Chromatin in Primary Human T Lymphocytes by ATAC-Seq
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Publisher Correction: scCASE: accurate and interpretable enhancement for single-cell chromatin accessibility

Songming Tang1, Xuejian Cui2, Rongxiang Wang3

  • 1School of Mathematical Sciences and LPMC, Nankai University, Tianjin, 300071, China.

Nature Communications
|March 13, 2024
PubMed
Abstract

No abstract available in PubMed .

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The histone proteins in the nucleosomes are post-translationally modified (PTM) to increase or decrease access to DNA. The commonly observed PTMs are methylation, acetylation, phosphorylation, and ubiquitination of lysine amino acids in the histone H3 tail region. These histone modifications have specific meaning for the cell. Hence, they are called "histone code". The protein complex involved in histone modification is termed as "reader-writer" complex.
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