Lutein Production and Extraction from Microalgae: Recent Insights and Bioactive Potential

Area of Science:

• Biotechnology
• Nutraceuticals
• Phycology

Background:

• Microalgae are recognized as potent sources of valuable bioactive compounds.
• Lutein, a significant pigment, offers numerous health benefits, particularly for ocular health.
• The increasing global population and aging demographics drive demand for lutein.

Purpose of the Study:

• To review methods for optimizing lutein extraction and production from microalgae.
• To summarize the reported bioactivities and health benefits of lutein.
• To explore strategies for enhancing lutein yield, including cultivation and genetic engineering.

Main Methods:

• Literature review of extraction optimization techniques.
• Compilation of studies on lutein's health-promoting bioactivities.
• Analysis of microalgae cultivation parameter adjustments and genetic modification approaches.

Main Results:

• Lutein exhibits significant antioxidant, anti-inflammatory, anticancer, and cardioprotective properties.
• Various methods, including altered culturing conditions and pilot-scale systems, enhance microalgal lutein production.
• Genetic engineering presents a potential avenue for further increasing lutein yield.

Conclusions:

• Optimized extraction and sustainable production methods are crucial for meeting the rising market demand for lutein.
• Microalgae represent a promising and eco-sustainable source for lutein production.
• Further research into genetic engineering and scaled-up cultivation is warranted.