Merkel cell carcinoma mimicking acute leukemia
Jonathan Keow1, Keith F Kwan2, Ben D Hedley2
1DynaLIFE Medical Labs, Edmonton, Alberta, Canada.
International Journal of Laboratory Hematology
|March 13, 2024
Abstract:
Bone marrow aspirate showed diffuse infiltration by a population of monomorphic cells with scant cytoplasm, markedly increased nuclear-to-cytoplasmic ratio, and numerous indistinct nucleoli. Bone marrow biopsy confirmed extensive marrow infiltration by a malignant neoplasm with strong and diffuse expression of synaptophysin by immunohistochemistry, consistent with metastases from Merkel Cell carcinoma.
