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Navigating Social Cognitive Impairments in Schizophrenia Spectrum Disorders: Protocol for a Pilot Pre-Post
Elisabeth Thibaudeau1,2, Elodie Peyroux3, Nicolas Franck3,4
1Department of Psychiatry, McGill University, Montreal, QC, Canada.
JMIR Research Protocols
|March 13, 2024
Summary
This study adapted the RC2S cognitive remediation program for remote delivery to individuals with schizophrenia spectrum disorder (SSD). The remote version shows promise for improving social cognition and daily functioning in SSD patients.
Area of Science:
- Psychiatry
- Neuroscience
- Rehabilitation
Background:
- Social cognitive impairments are common in schizophrenia spectrum disorder (SSD) and hinder daily functioning.
- Cognitive remediation (CR) improves social cognition but faces challenges in skill transfer and personalization.
- RC2S is a French CR program combining strategy learning and digital simulations, originally designed for in-person delivery.
Purpose of the Study:
- To culturally adapt the RC2S program for North American contexts (English and French-Canadian).
- To assess the feasibility, acceptability, safety, and implementation of a remote version of RC2S for individuals with SSD.
- To explore the preliminary effects of remote RC2S on goal attainment, social cognition, and psychosocial outcomes.
Main Methods:
- A pre-post quasi-experimental design was used.
- The RC2S program underwent translation and cultural adaptation.
- Twenty participants with SSD and 5 therapists received remote RC2S sessions, with assessments before and after the intervention.
Main Results:
- 45% of participants with SSD (9/20) and 5 therapists completed the study.
- Participants received a mean of 20.5 out of 24 biweekly sessions.
- Data on acceptability, feasibility, safety, and implementation were collected.
Conclusions:
- Improving social cognition is crucial for functional recovery in SSD.
- Digital delivery of CR interventions like remote RC2S can enhance ecological validity and accessibility.
- The remote adaptation of RC2S is a promising approach for managing social cognitive deficits in SSD.

