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Aflatoxin Biodetoxification Strategies Based on Postbiotics.

Nader Khani1,2, Ghasem Noorkhajavi3,4, Roya Abedi Soleiman2

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Probiotics and Antimicrobial Proteins
|March 13, 2024
PubMed
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Aflatoxins (AFs), dangerous food contaminants, can be detoxified using postbiotics. This review explores postbiotics

Keywords:
AflatoxinFood safetyMycotoxinsPostbioticProbiotics

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Area of Science:

  • Food Science and Technology
  • Mycology and Mycotoxicology
  • Public Health and Toxicology

Background:

  • Aflatoxins (AFs) are highly toxic secondary metabolites produced by fungi, posing significant food safety risks.
  • Human exposure to AFs occurs through direct consumption of contaminated food or indirect ingestion via animal products.
  • AF contamination presents substantial public health and economic challenges globally.

Purpose of the Study:

  • To review the concept and definition of aflatoxins (AFs).
  • To explore the benefits and biological role of postbiotics in AF detoxification.
  • To highlight the application of postbiotics in the food and pharmaceutical industries for mitigating AF risks.

Main Methods:

  • Review of existing literature on aflatoxins, mycotoxins, and detoxification strategies.
  • Analysis of the biological mechanisms of postbiotics in neutralizing AFs.
  • Examination of current and potential applications of postbiotics in food and pharmaceutical sectors.

Main Results:

  • Postbiotics demonstrate potential as effective agents for detoxifying AFs.
  • These compounds can alter or eradicate the molecular structure of AFs, reducing toxicity.
  • Postbiotics offer promising benefits for the food-pharmaceutical industry in managing AF contamination.

Conclusions:

  • Developing cost-effective strategies for AF detoxification is crucial.
  • Postbiotics represent a viable and beneficial approach for combating AF contamination.
  • Further research into postbiotics can enhance food safety and reduce economic losses associated with AFs.