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Updated: Jul 1, 2025
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Generation of Induced Regulatory T Cells from Primary Human Naïve and Memory T Cells
Published on: April 16, 2012
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Harnessing regulatory T cells to establish immune tolerance
Patrick Ho1, Ellen Cahir-McFarland2, Jason D Fontenot3
1Diabetes Center, University of California San Francisco, San Francisco, CA 94143, USA.
Science Translational Medicine
|March 13, 2024
Abstract
None:
Engineered regulatory T (Treg) cells have emerged as precision therapeutics aimed at inducing immune tolerance while reducing the risks associated with generalized immunosuppression. This Viewpoint highlights the opportunities and challenges for engineered Treg cell therapies in treating autoimmune and other inflammatory diseases.
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