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Updated: Aug 15, 2026

Methods for Detecting Cough and Airway Inflammation in Mice
Published on: August 2, 2024
Diagnosing chronic cough in patients involves a thorough history, physical exam, and imaging like chest roentgenograms. Pulmonary function tests and bronchoprovocation can further aid in identifying conditions like asthma or bronchitis.
Area of Science:
- Pulmonology
- Internal Medicine
Background:
- Cough is a prevalent symptom in patients presenting to physicians.
- Identifying the underlying cause is crucial for effective treatment.
Purpose of the Study:
- To outline diagnostic approaches for chronic cough in an outpatient setting.
- To highlight the utility of various clinical and laboratory procedures.
Main Methods:
- Comprehensive patient history and physical examination.
- Diagnostic imaging, including chest roentgenograms.
- Pulmonary function testing (PFTs) and bronchoprovocation challenges.
- Evaluation for chronic rhinosinusitis and postnasal drip.
Main Results:
- Chest roentgenograms can reveal infections (tuberculosis, fungal), bronchiectasis, lung abscess, or lung cancer.
- PFTs help differentiate obstructive (asthma, bronchitis) from restrictive (fibrosis) lung diseases.
- Bronchoprovocation testing aids in diagnosing conditions like cough-variant asthma when PFTs are normal.
- Chronic rhinosinusitis is a common cause, though often challenging to confirm diagnostically.
Conclusions:
- A majority of chronic cough cases can be diagnosed using standard outpatient clinical and laboratory methods.
- Integrated diagnostic strategies are essential for effective cough management.
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