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Updated: Jul 1, 2025

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A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
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Tree-Values: Selective Inference for Regression Trees
Anna C Neufeld1, Lucy L Gao2, Daniela M Witten3
1Department of Statistics, University of Washington, Seattle, WA 98195, USA.
Summary
This study introduces a new selective inference framework for Classification and Regression Trees (CART). The methods ensure reliable statistical guarantees for inference on CART model outputs, controlling error rates and coverage.
Area of Science:
- Statistics
- Machine Learning
- Data Mining
Background:
- Inference on Classification and Regression Trees (CART) requires specialized methods.
- Naive inference approaches fail to provide standard statistical guarantees like Type 1 error control.
Purpose of the Study:
- To develop a selective inference framework for fitted CART models.
- To ensure valid statistical inference, including error rate control and coverage, for CART outputs.
Main Methods:
- Proposing a selective inference framework by conditioning on the data used for tree estimation.
- Developing a test for mean response differences between terminal nodes controlling selective Type 1 error rate.
- Creating a confidence interval for mean response within a terminal node achieving nominal selective coverage.
- Providing efficient algorithms for computing necessary conditioning sets.
Main Results:
- The proposed framework successfully controls the selective Type 1 error rate for hypothesis tests.
- Confidence intervals achieve nominal selective coverage for mean responses within terminal nodes.
- Methods were validated through simulation studies and application to a real-world dataset.
Conclusions:
- The selective inference framework offers a statistically sound approach for analyzing CART models.
- These methods enhance the reliability of statistical inference in the context of machine learning algorithms.
- The approach is applicable to various datasets, including those in health and nutrition research.
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