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Subacute Thyroiditis Due to COVID-19 Vaccine
Nishant Kumar1, Dina Falah Zeki2,3, Mihail Zilbermint2,3,4
1Franciscan Health Olympia Fields, South, Crawford Ave, Olympia Fields, IL 60461, USA.
Journal of Community Hospital Internal Medicine Perspectives
|March 14, 2024
Summary
A 90-year-old female developed subacute thyroiditis after mRNA COVID-19 vaccination. This case highlights the importance of checking thyroid function in patients with encephalopathy following vaccination.
Area of Science:
- Endocrinology
- Vaccinology
- Neurology
Background:
- mRNA SARS-CoV-2 vaccines have been widely administered.
- Adverse events following vaccination require thorough investigation.
- Thyroid dysfunction can present with varied neurological symptoms.
Purpose of the Study:
- To report a rare case of subacute thyroiditis following mRNA COVID-19 vaccination.
- To emphasize the need for considering thyroid dysfunction in vaccine recipients presenting with neurological symptoms.
- To raise awareness among clinicians about potential acute vaccine complications.
Main Methods:
- Case report of a 90-year-old female admitted with confusion and weakness.
- Laboratory investigations including thyroid function tests (TSH, T4), ESR, and CRP.
- Thyroid ultrasonography and nuclear medicine thyroid uptake scan.
Main Results:
- The patient presented with low TSH, elevated T4, ESR, and CRP levels.
- Thyroid imaging revealed nodules and low uptake, consistent with subacute thyroiditis.
- Symptoms developed 19 days after the second mRNA SARS-CoV-19 vaccine dose.
Conclusions:
- Subacute thyroiditis is a potential acute complication of mRNA SARS-CoV-2 vaccination.
- Physicians should discuss vaccine risks and benefits, check thyroid function in patients with encephalopathy, and recognize hyperthyroidism symptoms.
- Further research is needed to identify individuals at higher risk for vaccine-related complications.
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