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Related Concept Videos

Morphogenesis02:19

Morphogenesis

Plant morphogenesis—the development of a plant’s form and structure—involves several overlapping developmental processes, including growth and cell differentiation. Precursor cells differentiate into specific cell types, which are organized into the tissues and organ systems that make up the functional plant.
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Capsule endoscopy, or wireless or video capsule endoscopy, is a diagnostic procedure for examining the entire gastrointestinal tract. Patients swallow a capsule about the size of a vitamin tablet. The capsule is equipped with a transmitter, a battery, an LED light source, and a color video camera to capture images throughout the gastrointestinal tract. This procedure is particularly useful for diagnosing conditions such as Crohn's disease, ulcerative colitis, tumors, polyps, ulcers, unexplained...

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MorphGI: A Self-Propelling Soft Robotic Endoscope Through Morphing Shape.

Julius E Bernth1, Guokai Zhang1, Dionysios Malas1

  • 1Department of Surgical and Interventional Engineering, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.

Soft Robotics
|March 14, 2024
PubMed
Summary
This summary is machine-generated.

The novel MorphGI robotic endoscope offers a safer, self-propelling alternative to conventional colonoscopes for bowel cancer detection. It demonstrated reduced insertion forces and efficient navigation in simulated colon environments.

Keywords:
MorphGI and self-propellingbowel cancercolonoscopy

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Area of Science:

  • Medical Devices
  • Robotics
  • Gastroenterology

Background:

  • Conventional colonoscopy, while effective for bowel cancer detection, has design limitations including rigidity and difficult maneuverability, leading to patient discomfort and potential injury.
  • Existing colonoscope technology has seen minimal innovation in fundamental design over several decades.

Purpose of the Study:

  • To introduce and evaluate the MorphGI, a novel robotic endoscope system designed for improved safety and ease of use in colonoscopy.
  • To assess the MorphGI's performance in terms of maneuverability, force reduction, and self-propulsion capabilities compared to conventional colonoscopes.

Main Methods:

  • The MorphGI system, featuring a soft, self-propelling robotic endoscope, underwent kinematic control verification.
  • Performance was evaluated using a benchtop colon simulator, a force-sensing colon simulator, and surgically removed pig colon tissue.

Main Results:

  • The MorphGI successfully completed colonoscopies in a simulator within an average of 10.84 minutes.
  • Compared to conventional colonoscopes, MorphGI demonstrated significant reductions in peak insertion forces (77% in high-stiffness mode, 62% in low-stiffness mode).
  • Self-propulsion was validated in excised tissue but not in live pigs due to anatomical discrepancies.

Conclusions:

  • The MorphGI robotic endoscope system exhibits core features demonstrating its potential as a safer and more manageable alternative for colonoscopy.
  • Further development is needed to address anatomical differences for successful in vivo application in human patients.