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NCI Cancer Research Data Commons: Cloud-Based Analytic Resources
David Pot1, Zelia Worman2, Alexander Baumann3
1General Dynamics Information Technology, Falls Church, Virginia.
The National Cancer Institute's Cloud Resources (CR) offer cloud-based tools and workspaces for analyzing large cancer datasets. Researchers can access, analyze, and integrate their own data within the Cancer Research Data Commons (CRDC) ecosystem.
Area of Science:
- Bioinformatics
- Computational Biology
- Cancer Research
Background:
- The Cancer Research Data Commons (CRDC) ecosystem facilitates cancer data analysis.
- Cloud Resources (CR) are key analytical components within the CRDC.
Purpose of the Study:
- To review the functionalities of the three NCI Cloud Resources.
- To highlight how CRs enable cloud-hosted cancer data analysis and integration.
Main Methods:
- Review of the NCI Cloud Resources: Broad Institute FireCloud, ISB Cancer Gateway, and Seven Bridges Cancer Genomics Cloud.
- Description of CR capabilities for data access, analysis, and user data integration.
Main Results:
- The three CRs provide access to large, multimodal cancer datasets hosted in the cloud.
- Users can perform in-situ data analysis without needing to download or store data.
- Researchers can upload their own data and tools to create custom analysis workflows.
Conclusions:
- NCI Cloud Resources empower researchers with scalable tools for cancer data analysis.
- The CRDC ecosystem, through its CRs, supports collaborative and integrated cancer research.
- These cloud platforms facilitate advanced computational analysis of complex cancer datasets.
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