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Cancer incidence among Armenians in California
Ani S Movsisyan Vernon1,2, Jeffrey S Hoch1,3, Laura Fejerman1,2
1Department of Public Health Sciences, University of California Davis, Davis, California, USA.
Cancer Medicine
|March 16, 2024
Summary
This study reveals elevated stomach, colorectal, and thyroid cancer incidence in California Armenians. Higher rates of tobacco-related cancers were also observed in Armenian males, highlighting a need for targeted research and interventions.
Area of Science:
- Oncology
- Epidemiology
- Public Health
Background:
- California has the largest Armenian population in the U.S.
- Previous cancer incidence data may be inaccurate due to misclassification of Armenians in databases.
- This is the first study to specifically examine cancer incidence in California's Armenian population.
Purpose of the Study:
- To investigate cancer incidence patterns among Armenians in California.
- To compare cancer incidence in Armenians to non-Hispanic Whites (NHWs).
- To identify specific cancer types with potentially higher incidence in the Armenian population.
Main Methods:
- Utilized the California Cancer Registry (1988-2019) and an Armenian Surname List to identify cases.
- Calculated proportional incidence ratios (PIR) comparing Armenians to NHWs.
- Conducted exploratory incidence rate ratio (IRR) analyses using American Community Survey (ACS) population data (2006-2015).
Main Results:
- Identified 27,212 cancer diagnoses among Armenians.
- Armenian males showed significantly higher PIR for stomach, thyroid, bladder, colorectal, and lung cancers.
- Armenian females exhibited higher PIR for stomach, thyroid, and colorectal cancers.
- Exploratory IRR analyses confirmed higher incidence for stomach, bladder, and colorectal cancers in males, and stomach cancer in females.
Conclusions:
- Observed elevated incidence of stomach, colorectal, and thyroid cancers in both Armenian males and females.
- Higher incidence of tobacco-related cancers was noted among Armenian males.
- Further research is recommended to improve Armenian population estimates and investigate cancer risk factors.
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