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Related Concept Videos

Infertility in Males01:23

Infertility in Males

262
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
262
Infertility in Females01:28

Infertility in Females

292
Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...
292
In Vitro Fertilization01:24

In Vitro Fertilization

258
In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
258
Birth Control Methods01:22

Birth Control Methods

246
Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although...
246

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Updated: Jun 30, 2025

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
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Best Practice Recommendations for Infertility Management.

Jaideep Malhotra1, M Gouri Devi2, Madhuri Patil3

  • 1Managing Director - Rainbow IVF, Agra, U.P., President ISAR (2019).

Journal of Human Reproductive Sciences
|March 18, 2024
PubMed
Summary
This summary is machine-generated.

This guide offers recent advances and management strategies for sub-fertility, aiding healthcare professionals in making evidence-based clinical decisions for patient care.

Keywords:
ICSIIUIIVFInfertilityendocrinopathiesethical issuesfertility preservationgeneticsinvestigationsovulatory disorderspolycystic ovary syndromepoor respondersrecurrent implantation failuresafetythird party reproductionultrasoundunexplained infertility

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Area of Science:

  • Reproductive Medicine
  • Infertility Management

Background:

  • Sub-fertility affects numerous couples globally, necessitating updated clinical guidance.
  • Advances in reproductive medicine require continuous professional development for specialists.

Purpose of the Study:

  • To provide comprehensive guidance on sub-fertility management.
  • To update healthcare professionals on recent advances in reproductive medicine.
  • To support clinical decision-making with the best available evidence.

Main Methods:

  • Systematic literature review up to June 2019 (PubMed, Cochrane).
  • Inclusion of international guidelines, cohort studies, case series, observational studies, and RCTs.
  • Review of available Indian data and expert consensus deliberations.

Main Results:

  • Identification of areas with inconsistent, insufficient, or non-existent evidence.
  • Emphasis on the need for future research, particularly well-designed RCTs.
  • Consideration of the Indian context, including facilities, costs, and insurance.

Conclusions:

  • Recommendations are designed to aid infertility specialists, gynecologists, embryologists, and counselors.
  • The guidance aims to improve the appropriate and effective care of patients with sub-fertility.
  • Future research is crucial for establishing evidence-based practices in reproductive medicine.