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Updated ACVIM consensus statement on equine herpesvirus-1.

David P Lunn1, Brandy A Burgess2, David C Dorman3

  • 1School of Veterinary Science, University of Liverpool, Liverpool, United Kingdom.

Journal of Veterinary Internal Medicine
|March 18, 2024
PubMed
Summary
This summary is machine-generated.

Equine herpesvirus-1 (EHV-1) causes significant equid diseases like abortion and EHM. Evidence for effective EHV-1 vaccines and treatments remains limited, necessitating improved research.

Keywords:
abortiondiagnosisequineequine herpesvirus myeloencephalopathyherpesvirus‐1rhinopneumonitistherapyvaccinationviremia

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Area of Science:

  • Veterinary Virology
  • Equine Infectious Diseases

Background:

  • Equine herpesvirus-1 (EHV-1) is a common and serious pathogen in horses.
  • Clinical outcomes include abortion and equine herpesvirus myeloencephalopathy (EHM).
  • A 2009 consensus statement requires updating due to new research and veterinary needs.

Purpose of the Study:

  • To revise the 2009 consensus statement on EHV-1.
  • To systematically review current knowledge on EHV-1 vaccination, treatment, pathogenesis, and diagnostics.

Main Methods:

  • Four systematic reviews formed the basis of this updated consensus statement.
  • Key questions regarding EHV-1 management were addressed.

Main Results:

  • Limited evidence supports the efficacy of current EHV-1 vaccination strategies.
  • Effective pharmaceutical treatments for EHV-1 infection are not well-established.
  • Improvements in experimental design and reporting are crucial for future EHV-1 research.

Conclusions:

  • The current consensus on EHV-1 management requires significant updates.
  • Further high-quality research is essential to improve EHV-1 control and treatment outcomes.